you would want to make sure that OB is not currently connected when you do the easel connection, but If it’s working in OB then the most common issue for it not being able to connect to Easel is the Easel Driver missing.
You can check that the driver is installed correctly by selecting Machine>Advanced>Machine Inspector and you should be able to see the easel driver version in that popup (shown in the photo below)
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If the driver is correct and you are still having trouble, try performing the machine setup again, here are some tips on doing that setup for your specific CNC:
